Mirzajani A, Barat A, Abolghasemi J. Intraocular Pressure Changes Before and After Presbyopic Optical Correction in Early Presbyopic Adults. Func Disabil J 2025; 8 (1)
URL:
http://fdj.iums.ac.ir/article-1-312-en.html
1- Department of Optometry, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran. , Mirzajani.a@iums.ac.ir
2- Department of Optometry, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran.
3- Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Abstract: (36 Views)
Background and Objectives: This study aims to evaluate the effects of optical correction of presbyopia on intraocular pressure (IOP) in newly diagnosed presbyopic individuals aged 40 to 50 years. While the physiological mechanisms underlying presbyopia and IOP regulation have been well documented independently, the interaction between accommodative correction and short-term pressure dynamics remains poorly understood.
Methods: A total of 40 participants (18 males, 22 females) with newly diagnosed presbyopia and no history of ocular diseases were recruited for this cross-sectional study. All participants underwent comprehensive baseline eye exams, including IOP measurement via Goldmann applanation tonometry. Optical correction of presbyopia was prescribed, and IOP was reassessed after 7 days of consistent use. The cohort was stratified by age (40–44 and 45–50 years) and initial IOP to assess subgroup effects.
Results: Paired t-test analysis revealed a statistically significant reduction in mean IOP following correction, with overall IOP decreasing from 15.72±3.17 to 15.35±2.83 mm Hg (mean difference: 0.37±0.89 mm Hg; P=0.01). The decrease was also significant in the 45–50 age group (mean difference: 0.45±0.80 mm Hg; P=0.01), whereas the 40–44 age group showed no significant change (P=0.26). The McNemar test indicated a significant decrease in the proportion of participants with IOP≥16 mm Hg after correction (P=0.03).
Conclusion: The optical correction of presbyopia was associated with a small but statistically significant short-term reduction in IOP, particularly in older participants and those with elevated initial pressure. These findings suggest that accommodative demand and visual strain may transiently influence ocular pressure, meriting further research.
Type of Study:
Research |
Subject:
Optometry Received: 2025/03/7 | Accepted: 2025/06/11 | Published: 2025/03/2