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Showing 7 results for Multiple Sclerosis

Atefeh Saadati Qamsari, Shohreh Noorizadeh Dehkordi, Mehdi Dadgoo,
Volume 1, Issue 4 (12-2018)
Abstract

Background & Objectives: The purpose of this study was to identify the experiences of people with multiple sclerosis (MS) from mobility barriers they are faced with.
Methods: This study included 13 patients with MS (7 women and 6 men), with informed consent, whose average age is 43 years. A qualitative content analysis approach was used. According to the EDSS criteria, the severity of their disability was between 8-4. The sampling was carried out purposefully with maximum variation, and the data was collected through semi-structured in-depth interviews. Immediately after each interview, the data was analyzed using the Cheevakumjorn`s method. 
Results: After analyzing the obtained data and categorizing the resulting codes; three main categories were observed: “disease-affected barriers”, “personal barriers” and “environmental barriers”. The data of each theme were classified as subthemes. 
Conclusion: Based on research findings and experiences of the participants, rehabilitation specialists during the assessment, management and treatment of patients with MS should alert and educate patients about personal mobility barriers and try to help them fit in their physical environment.
 

Ghazal Roshdi, Shohreh Noorizadeh Dehkordi, Mehdi Dadgoo,
Volume 3, Issue 1 (2-2020)
Abstract

Background and Objectives: This study aimed to identify the experiences of women with Multiple Sclerosis (MS) about urinary dysfunctions consequences.
Methods: This qualitative study with the content analysis approach included 10 women with MS (age range: 29 to 59 years), who were recruited using a purposive sampling method with maximum variation. Through semi-structured in-depth interviews, the participants explained their experiences of urinary dysfunctions consequences. The obtained data were analyzed based on the content analysis method of Graneheim and Lundman.
Results: The content analysis revealed three key themes: Physical consequences, psycho-emotional consequences, and economic consequences.
Conclusion: Urinary dysfunctions cause widespread physical, psychological, and economic problems for women with MS. Therefore, treatment staff should address the MS patient’s concerns caused by urinary dysfunctions, in a non-threatening atmosphere, and help them to fearlessly manage their urinary problems.
 
Fatemeh Motaharinezhad, Shahriar Parvaneh, Setareh Ghahari,
Volume 3, Issue 1 (2-2020)
Abstract

Background and Objectives: Walking disorder is one of the most important manifestations of multiple sclerosis (MS), and indicates the progression of the disease. Fatigue and walking are considered as key symptoms affecting the patient’s quality of life. Therefore, this study aimed to investigate the relationship between walking status and fatigue, in people with MS.
Methods: A total number of 60 Iranian patients with MS completed the Persian version of the Multiple Sclerosis Walking Scale-12 (MSWS-12), the Modified Fatigue Impact Scale, and the Hospital Anxiety and Depression Scale. Data were analyzed using SPSS V. 20 software. The multivariate correlation and linear regression analyses were conducted to investigate the relationship between fatigue, anxiety, depression, demographic characteristics, and MSWS-12 scores.
Results: Gait problems were observed in 46.7% of the study participants. Also, the MSWS-12 scores were significantly associated with fatigue severity (P=0.001), in these patients. Moreover, depression, cognitive status, anxiety, and gait status were the most important factors affecting fatigue.
Conclusion: According to the present results, the presence of depression, cognitive problems, anxiety, and gait disorders are the most important factors affecting fatigue, in patients with MS.
 
Zahra Ghafari, Shohreh Noorizadeh Dehkordi, Afsaneh Nikjooy, Seyedeh Roghayeh Mousavi Khatir, Mehdi Moghaddasi,
Volume 5, Issue 1 (2-2022)
Abstract

Background and Objectives: More than 50% of multiple sclerosis (MS) patients suffer from urinary disorders. Exercise therapy is one of the first lines of treatment for urinary disorders in people with MS. This study evaluated the effectiveness of pelvic floor muscle exercise at home on quality of life (QoL) and fatigue in MS women with urinary disorders.
Methods: A randomized, double-blinded, controlled trial was conducted. Thirty women with relapsing and remitting urinary incontinence participated for eight weeks (daily) in this study. The participants were randomly divided into intervention (n=15) and control groups (n=15). The participants of the intervention group received common medicines and specific exercises for the pelvic floor. The control group used only conventional drugs during the study.
Results: The results showed significant differences in all variables related to fatigue and QoL in the intervention group (P<0.05). But no significant difference was found in any of the variables related to fatigue and QoL in the control group (P>0.05). However, in the intervention group, significant differences were found in the total score of the QoL and the three subgroups (bothered, worry, and restricted) (P<0.05). In addition, the results showed a significant difference in the cognitive, physical, and psycho-social subgroups in the fatigue questionnaire (P<0.05). The fatigue scores and QoL in the intervention group compared to the control group showed a significant difference (P<0.05).
Conclusion: It seems that pelvic floor exercises at home reduce fatigue and improve QoL in women with MS with urinary incontinence. Although the total score of fatigue between the two groups was not significant, the results in the intervention group showed significant results and it seems that by controlling the intervening factors, a significant difference can be observed in the total score of fatigue between the two groups. Therefore, we demonstrated that pelvic floor muscle exercises in women suffering from urinary incontinence improve urinary incontinence and reduce fatigue, and improve the QoL.

Atefeh Saadati Qamsari, Shohreh Noorizadeh Dehkordi, Mehdi Dadgoo,
Volume 6, Issue 1 (2-2023)
Abstract

Background and Objectives: The complications and motor disorders caused by multiple sclerosis (MS) not only affect the individual’s movement abilities but also play a crucial and valuable role in how these individuals carry out their daily activities. In this way, patients with MS use certain compensatory methods, depending on individual differences, their environment, and their family’s support, to help with the complications of this disorder. For this reason, this study aims to identify the compensatory strategies that people with MS use to adapt to their mobility limitations. 
Methods: In this study, 13 patients with MS (7 women and 6 men), with informed consent, an average age of 43 years, and a qualitative content analysis approach, were included in the study. The sampling was performed purposefully with maximum variation, and the data was collected via quasi-structured in-depth interviews. Immediately after each interview, the data was analyzed using Cheevakumjorn`s method. 
Results: After analyzing the data and extracting the resulting codes, the codes were classified according to their similarities and differences. Ultimately, three main components of “compensatory strategies for home mobility”, “compensatory strategies for outdoor mobility”, and “compensatory strategies for carrying out daily activities” were formed. 
Conclusion: Although families play a major role in compensating for the mobility problems of these patients, it is necessary for health providers to reduce the burden placed on their families, and to educate MS people on self-care and adjust their living environment. Furthermore, providing mobility assistive devices for the patients should be done according to their differences and their environment. 

 
Ms Mahya Eshghi, Dr. Malahat Akbarfahimi, Ghorban Taghizadeh Hajlouee, Elahe Hojati Abed,
Volume 7, Issue 1 (3-2024)
Abstract

Background and Objectives: Occupational identity (OI) is a crucial factor in occupational therapy evaluations and interventions which is not investigated in chronic conditions, including multiple sclerosis (MS). The Occupatinal Identity Questionnaire (OIQ) is an appropriate tool for assessing occupational identity. As a result, this research aims to adapt the Persian version of OIQ for people with MS and evaluate its face and content validity. 
Methods: The face validity of OIQ was qualitatively and quantitatively evaluated with 15 participants diagnosed with MS. Interviews were used to qualitatively assess the face validity. In addition, the item impact method (IIM) was applied to quantitatively assess face validity. A total of 12 experts with experience in the field of neurology participated in evaluating content validity. The content validity ratio (CVR) and the content validity index (CVI) were applied in this evaluation. 
Results: All the items received IIM scores above 1.5 (3.03 to 4.62). Also, none of the items were mentioned as incomprehensible during interviews. The CVR scores for each item ranged from 0.63 to 1 (based on Lawshe >0.59). After that stage, a CVI study was conducted. In that study, scores for each item ranged from 0.83 to 1. S-CVI/Ave score was 0.94 and scale CVI/universal agreement (S-CVI/UA) was 0.57. Based on experts’ comments, it was determined that adjustments were necessary for item number 6 and 10. 
Conclusion: The Persian version of the OIQ demonstrates acceptable face and content validity in the context of MS. It is recommended to conduct a test re-test, internal consistency, construct validity, and factor analysis. 
 
Negar Balali, Ashkan Irani, Seyed Mansoor Rayegani,
Volume 8, Issue 1 (3-2025)
Abstract

Background and Objectives: Falls are a common issue among persons with multiple sclerosis (MS), and cognitive function is variably affected by the disease. Cognitive impairments impact various aspects of life, including quality of life, safety (fall risk and driving), and participation. This study aims to examine the relationship between executive function, cognitive skills, and fall risk in persons with multiple sclerosis.
Methods: Studies examining the relationship between falls and cognitive performance were reviewed using databases, such as Google Scholar, PubMed, and Science Direct, with keywords, including cognitive impairment, executive function, fall risk, and multiple sclerosis.
Results: Cognitive skills associated with fall risk include information processing speed, ability to switch between tasks, cognitive flexibility, response inhibition, working memory, and visuospatial memory. However, verbal fluency is not associated with fall risk.
Conclusion: Executive function is related to fall risk in persons with multiple sclerosis; the greater the cognitive impairments, the higher the likelihood of falls in these individuals.
 


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