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Balali N, Irani A, Rayegani S M. Cognitive Impairment and Fall Risk in Multiple Sclerosis: A Review Study. Func Disabil J 2025; 8 (1)
URL: http://fdj.iums.ac.ir/article-1-292-en.html

Background and Objectives: Falls are a common issue among persons with multiple sclerosis (MS), and cognitive function is variably affected by the disease. Cognitive impairments impact various aspects of life, including quality of life, safety (fall risk and driving), and participation. This study aims to examine the relationship between executive function, cognitive skills, and fall risk in persons with multiple sclerosis.
Methods: Studies examining the relationship between falls and cognitive performance were reviewed using databases, such as Google Scholar, PubMed, and Science Direct, with keywords, including cognitive impairment, executive function, fall risk, and multiple sclerosis.
Results: Cognitive skills associated with fall risk include information processing speed, ability to switch between tasks, cognitive flexibility, response inhibition, working memory, and visuospatial memory. However, verbal fluency is not associated with fall risk.
Conclusion: Executive function is related to fall risk in persons with multiple sclerosis; the greater the cognitive impairments, the higher the likelihood of falls in these individuals.