en بینایی سنجی Optometry پژوهشي Research <strong>Background and Objectives</strong>: The prolonged use of digital screens can cause a set of visual and ocular symptoms known as Computer Vision Syndrome (CVS), which is a common health issue among computer users. This study aimed to estimate the prevalence of CVS among university employees and graduate students in their occupational environment in Iran.<br> <strong>Methods</strong>: A cross-sectional study was carried out in the Rehabilitation School of Iran University of Medical Science, Tehran, Iran. The study population (n=154) included all university employees and graduate students who spend at least one hour of computer work per day in their workplace. The participants completed a validated self-administered questionnaire. A descriptive analysis was performed and the prevalence of CVS was calculated. The correlations between variables were assessed using the Pearson and Spearman correlation coefficients and non-parametrical tests were used to evaluate the association between CVS and predictor variables, as well as differences between subgroups.&nbsp;<br> <strong>Results</strong>: The Mean&plusmn;SD age of the sample was 37.7&plusmn;11.0 years, 64.3% were women, 57.8% were employee, 56.5% have higher education and the Mean&plusmn;SD of computer usage time was 5.08&plusmn;2.2. The total prevalence of CVS was 48.7% and the most frequent symptoms were eye redness (62.3%) and burning (56.5%). A significant positive correlation was found between the number of hours working with a computer and the total score of CVS (Pearson correlation coefficient = 0.248, P=0.02). Moreover, the total score of CVS significantly differed between participants who use six or more hours the computer and those who spend less than six hours (Mann-Whitney U test: P=0.007).&nbsp;<br> <strong>Conclusion</strong>: This is the first investigation using a validated questionnaire to estimate the prevalence of CVS among computer users in the occupational environment, in Iran. The results show a relatively high prevalence of CVS these populations. The most affected are those who use the computer for a longer duration.<br> &nbsp; Computer vision syndrome, Digital eye strain, Ocular symptoms, Occupational hazards 151 160 http://fdj.iums.ac.ir/browse.php?a_code=A-10-159-1&slc_lang=en&sid=1 Milad Qolami qolami.m@iums.ac.ir 10031947532846002015 10031947532846002015 No Department of Optometry, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran. Natalia Cantó-Sancho 10031947532846002016 10031947532846002016 No Department of Optics, Pharmacology and Anatomy, University of Alicante, San Vicente del Raspeig, Alicante, Spain. Mar Seguí-Crespo 10031947532846002017 10031947532846002017 No Department of Optics, Pharmacology and Anatomy, University of Alicante, San Vicente del Raspeig, Alicante, Spain - Public Health Research Group, University of Alicante, Alicante, Spain. Elena Ronda-Pérez 10031947532846002018 10031947532846002018 No Public Health Research Group, University of Alicante, Alicante, Spain - Biomedical Research Center Network for Epidemiology and Public Health (CIBERESP), Madrid, Spain. Ali Mirzajani mirzajani.a@iums.ac.ir 10031947532846002019 10031947532846002019 Yes Department of Optometry, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran. Ghorban Taghizade gh_taghizade@yahoo.com 10031947532846002020 10031947532846002020 No Department of Occupational Therapy, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran.